The flagship of Costa's ever-growing fleet, the Costa Serena features a number of modern amenities and grade options not always found on other Costa vessels. Highlights include but are not limited to: spa-grade cabins and dining, an impressive waterslide, two magrodome-covered pools and a huge screen for showing movies on deck. Serena offers a variety of Mediterranean itineraries and sails primarily out of Venice and Savona.
Mediterranean Western | Interior | Oceanview | Balcony | Suite | |
| 08/05/2014 | | $1,299 | $1,499 | $1,799 | $2,499 |
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| 08/08/2014 | | $1,299 | $1,499 | $1,799 | $2,199 |
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| 08/09/2014 | | $1,299 | $1,499 | $1,799 | $2,199 |
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| 08/10/2014 | | $1,099 | $1,299 | $1,499 | $2,199 |
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| 08/11/2014 | | $1,299 | $1,299 | $1,499 | $2,199 |
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| 08/12/2014 | | $1,299 | $1,499 | $1,799 | $2,499 |
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| 08/15/2014 | | $1,199 | $1,429 | $1,729 | $2,099 |
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| 08/16/2014 | | $1,199 | $1,429 | $1,729 | $2,099 |
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| 08/17/2014 | | $1,099 | $1,199 | $1,429 | $2,099 |
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| 08/18/2014 | | $1,199 | $1,199 | $1,429 | $2,099 |
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| 08/19/2014 | | $1,199 | $1,429 | $1,729 | - |
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| 08/22/2014 | | $1,199 | $1,429 | $1,729 | $2,099 |
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| 08/23/2014 | | $1,199 | $1,429 | $1,729 | $2,099 |
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| 08/24/2014 | | $799 | $1,199 | $1,429 | $2,099 |
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| 08/25/2014 | | $799 | $899 | $1,049 | $2,099 |
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| 08/26/2014 | | $1,049 | $1,199 | $1,429 | $2,399 |
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| 08/29/2014 | | $899 | $1,049 | $1,249 | $1,879 |
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| 08/30/2014 | | $899 | $1,049 | $1,249 | $1,879 |
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| 08/31/2014 | | $799 | $899 | $1,049 | $1,879 |
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| 09/01/2014 | | $799 | $899 | $1,049 | $1,879 |
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| 09/02/2014 | | $899 | $1,049 | $1,249 | $1,979 |
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| 09/05/2014 | | $799 | $899 | $1,049 | $1,979 |
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| 09/06/2014 | | $899 | $1,049 | $1,249 | $1,879 |
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| 09/07/2014 | | $799 | $899 | $1,049 | $1,879 |
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| 09/08/2014 | | $799 | $899 | $1,049 | $1,899 |
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| 09/09/2014 | | $919 | $1,069 | $1,269 | $1,999 |
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| 09/12/2014 | | $799 | $899 | $1,049 | $1,879 |
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| 09/13/2014 | | $1,049 | $1,249 | $1,549 | $1,879 |
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| 09/14/2014 | | $799 | $899 | $1,049 | $1,879 |
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| 09/16/2014 | | $899 | $1,049 | $1,249 | $1,879 |
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| 09/17/2014 | | $899 | $1,049 | $1,249 | - |
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| 09/19/2014 | | $699 | $799 | $949 | $1,729 |
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| 09/20/2014 | | $799 | $949 | $1,149 | $1,729 |
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| 09/21/2014 | | $699 | $799 | $949 | $1,729 |
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| 09/23/2014 | | $699 | $799 | $949 | $1,729 |
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| 09/24/2014 | | $799 | $949 | $1,149 | $1,829 |
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| 09/26/2014 | | $799 | $949 | $1,149 | $1,729 |
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| 09/27/2014 | | $799 | $949 | $1,149 | $1,729 |
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| 09/28/2014 | | $699 | $799 | $949 | $1,729 |
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| 09/30/2014 | | $599 | $699 | $849 | $1,729 |
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| 10/01/2014 | | $799 | $949 | $1,149 | $1,829 |
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| 10/03/2014 | | $599 | $699 | $849 | $1,629 |
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| 10/04/2014 | | $699 | $849 | $1,049 | $1,629 |
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| 10/05/2014 | | $599 | $699 | $849 | $1,629 |
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| 10/07/2014 | | $599 | $699 | $849 | $1,629 |
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| 10/08/2014 | | $699 | $849 | $1,049 | $1,729 |
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| 10/10/2014 | | $699 | $849 | $1,049 | $1,629 |
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| 10/11/2014 | | $699 | $849 | $1,049 | $1,629 |
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| 10/12/2014 | | $599 | $699 | $849 | $1,629 |
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| 10/14/2014 | | $549 | $649 | $849 | $1,629 |
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| 10/15/2014 | | $699 | $849 | $1,049 | $1,729 |
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| 10/17/2014 | | $549 | $649 | $849 | $1,629 |
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| 10/18/2014 | | $649 | $849 | $1,049 | $1,629 |
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| 10/19/2014 | | $549 | $649 | $849 | $1,629 |
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| 10/21/2014 | | $549 | $649 | $849 | $1,629 |
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| 10/22/2014 | | $649 | $849 | $1,049 | $1,729 |
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| 10/24/2014 | | $549 | $649 | $849 | $1,629 |
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| 10/25/2014 | | $649 | $849 | $1,049 | $1,629 |
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| 10/26/2014 | | $549 | $649 | $849 | $1,629 |
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| 10/28/2014 | | $549 | $599 | $749 | $1,629 |
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| 10/29/2014 | | $649 | $849 | $1,049 | $1,729 |
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| 10/31/2014 | | $549 | $599 | $749 | $1,629 |
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| 11/01/2014 | | $599 | $749 | $949 | $1,529 |
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| 11/02/2014 | | $549 | $599 | $749 | $1,529 |
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| 11/04/2014 | | $549 | $599 | $749 | $1,629 |
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| 11/05/2014 | | $599 | $749 | $949 | $1,629 |
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| 11/07/2014 | | $549 | $599 | $749 | $1,529 |
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| 11/08/2014 | | $599 | $749 | $949 | $1,529 |
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| 11/09/2014 | | $549 | $599 | $749 | $1,529 |
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| 11/11/2014 | | $499 | $549 | $749 | $1,529 |
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| 11/12/2014 | | $599 | $749 | $949 | $1,629 |
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| 11/14/2014 | | $499 | $549 | $749 | $1,529 |
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| 11/15/2014 | | $549 | $749 | $949 | $1,529 |
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| 11/16/2014 | | $499 | $549 | $749 | $1,529 |
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Middle East | Interior | Oceanview | Balcony | Suite | |
| 11/23/2014 | | $1,359 | $1,889 | - | $3,709 |
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| 11/24/2014 | | Contact cruise line for pricing & availability |
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| 12/12/2014 | | $699 | $799 | $999 | $1,559 |
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| 12/19/2014 | | $999 | $1,249 | $1,549 | $2,129 |
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| 12/26/2014 | | $1,199 | $1,399 | $1,799 | $2,329 |
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| 01/02/2015 | | $799 | $999 | $1,149 | $1,659 |
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| 01/09/2015 | | $699 | $899 | $1,049 | $1,559 |
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| 01/16/2015 | | $699 | $899 | $1,049 | $1,559 |
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| 01/23/2015 | | $699 | $899 | $1,049 | $1,559 |
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| 01/30/2015 | | $749 | $949 | $1,099 | $1,599 |
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| 02/06/2015 | | $749 | $949 | $1,099 | $1,599 |
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| 02/13/2015 | | $799 | $949 | $1,099 | $1,659 |
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| 02/20/2015 | | $799 | $949 | $1,099 | $1,659 |
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| 02/27/2015 | | $869 | $999 | $1,149 | $1,729 |
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| 03/06/2015 | | $869 | $999 | $1,149 | $1,729 |
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| 03/13/2015 | | $869 | $999 | $1,149 | $1,729 |
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| 03/20/2015 | | $869 | $999 | $1,149 | $1,729 |
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| 03/27/2015 | | $869 | $999 | $1,149 | $1,729 |
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The Orient | Interior | Oceanview | Balcony | Suite | |
| 04/03/2015 | | $1,889 | $2,299 | $2,849 | $3,629 |