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Central America & Panama Canal Cruises
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Showing 131 - 140 of 250 Cruises
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Add to Compare
16 Night Central America & Panama Canal Cruise from Miami, FL
Regent Seven Seas Cruises Seven Seas Grandeur
Departure Port:
Miami, FL
OCG Class
Luxury
Cruises to: GEORGE TOWN; CARTAGENA; PUNTARENAS; PUERTO QUETZAL; ACAPULCO; CABO SAN LUCAS; SAN DIEGO
more ...
Departing
Interior
Oceanview
Balcony
Suite
Dec 29, 2026
-
-
-
$12,203
Add to Compare
16 Night Central America & Panama Canal Cruise from Miami, FL
Regent Seven Seas Cruises Seven Seas Prestige
Departure Port:
Miami, FL
OCG Class
Luxury
Cruises to: GEORGE TOWN; CARTAGENA; PANAMA CANAL DAYLIGHT TRANSIT; PUNTARENAS; PUERTO QUETZAL; ACAPULCO; CABO SAN LUCAS
more ...
Departing
Interior
Oceanview
Balcony
Suite
Feb 7, 2029
-
-
-
$9,791
Add to Compare
16 Night Central America & Panama Canal Cruise from Miami, FL
Regent Seven Seas Cruises Seven Seas Splendor
Departure Port:
Miami, FL
OCG Class
Luxury
Cruises to: OCHO RIOS; CARTAGENA; PANAMA CANAL DAYLIGHT TRANSIT; PUNTARENAS; PUERTO QUETZAL; PUERTO VALLARTA; CABO SAN LUCAS
more ...
Departing
Interior
Oceanview
Balcony
Suite
Dec 20, 2027
-
-
-
$9,109
Add to Compare
16 Night Central America & Panama Canal Cruise from Mobile, AL
Carnival Cruise Line Carnival Spirit
Departure Port:
Mobile, AL
OCG Class
Mainstream
Cruises to: Cartagena, Colombia (dock); Puntarenas, Costa Rica (dock); Cabo San Lucas, Mexico (tender); Seattle, Wa (dock)
Departing
Interior
Oceanview
Balcony
Suite
Mar 29, 2027
Contact cruise line for pricing & availability
Add to Compare
16 Night Central America & Panama Canal Cruise from Port Canaveral, FL
Princess Cruises Star Princess
Departure Port:
Port Canaveral, FL
OCG Class
Mainstream
Cruises to: GRAND TURK, TURKS & CAICOS; ARUBA; FUERTE AMADOR, PANAMA (FOR PANAMA CITY); MAZATLAN, MEXICO; CABO SAN LUCAS, MEXICO; LOS ANGELES, CALIFORNIA
Departing
Interior
Oceanview
Balcony
Suite
Apr 7, 2028
$955
$1,255
$1,755
$2,705
Add to Compare
16 Night Central America & Panama Canal Cruise from San Diego, CA
Holland America Line Eurodam
Departure Port:
San Diego, CA
OCG Class
Premium
Cruises to: CABO SAN LUCAS, MEXICO; ACAPULCO, GUERRERO, MEXICO; HUATULCO, MEXICO; PUERTO CHIAPAS, MEXICO; PUERTO QUETZAL, GUATEMALA; PUNTARENAS (PUERTO CALDERA), COSTA RICA; ORANJESTAD, ARUBA
more ...
Departing
Interior
Oceanview
Balcony
Suite
Oct 8, 2026
$659
$829
$1,829
$4,199
Oct 7, 2027
$1,704
$1,974
$3,214
$5,494
Add to Compare
16 Night Central America & Panama Canal Cruise from San Diego, CA
Holland America Line Nieuw Amsterdam
Departure Port:
San Diego, CA
OCG Class
Premium
Cruises to: PUERTO VALLARTA, MEXICO; HUATULCO, MEXICO; PUERTO CHIAPAS, MEXICO; PUERTO QUETZAL, GUATEMALA; ACAJUTLA, EL SALVADOR; CARTAGENA, COLOMBIA; RELAXAWAY HALF MOON CAY, BAHAMAS
more ...
Departing
Interior
Oceanview
Balcony
Suite
Oct 2, 2026
$429
$589
$1,559
$3,839
Add to Compare
16 Night Central America & Panama Canal Cruise from San Diego, CA
Norwegian Cruise Line Norwegian Star
Departure Port:
San Diego, CA
OCG Class
Mainstream
Cruises to: CABO SAN LUCAS, MEXICO; ACAPULCO, MEXICO; PUERTO QUETZAL, GUATEMALA; PUNTARENAS PUERTO CALDERA, COSTA RICA; PANAMA CITY (PCT), PANAMA; CARTAGENA COLOMBIA; GEORGE TOWN, CAYMAN ISLANDS
more ...
Departing
Interior
Oceanview
Balcony
Suite
Feb 13, 2027
Contact cruise line for pricing & availability
Add to Compare
16 Night Central America & Panama Canal Cruise from San Diego, CA
Princess Cruises Island Princess
Departure Port:
San Diego, CA
OCG Class
Mainstream
Cruises to: PUERTO VALLARTA, MEXICO; HUATULCO, MEXICO; PUERTO CHIAPAS, MEXICO; PUNTARENAS, COSTA RICA; FUERTE AMADOR, PANAMA (FOR PANAMA CITY); ARUBA; FT. LAUDERDALE, FLORIDA
Departing
Interior
Oceanview
Balcony
Suite
Jan 29, 2027
$895
$965
$2,265
$2,825
Add to Compare
16 Night Central America & Panama Canal Cruise from San Diego, CA
Princess Cruises Island Princess
Departure Port:
San Diego, CA
OCG Class
Mainstream
Cruises to: Puerto Vallarta; Huatulco; Puerto Chiapas; Puntarenas; Fuerte Amador; Aruba; Fort Lauderdale (Miami)
Departing
Interior
Oceanview
Balcony
Suite
Jan 29, 2027
Contact cruise line for pricing & availability
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