American Cruise Lines is set to operate its largest-ever Mississippi River season in 2025, deploying five riverboats across more than 12 different itineraries that span 10 states from Louisiana to Minnesota. The season begins Feb. 21 onboard American Serenade, sailing a nine-day Lower Mississippi River Cruise between New Orleans and Memphis.
New for 2025 are several routes including a 12-Day Mississippi Explorer Cruise from Memphis to New Orleans and a 16-Day Grand Ohio River Cruise from Pittsburgh to St. Louis. The company is also introducing two extended voyages: a 51-Day Great United States Cruise and a 36-Day Civil War Battlefields Cruise, which will cover either the entire Mississippi or major sections of it along with other U.S. waterways.
The company's vessels, which include both paddlewheelers and modern riverboats, will operate itineraries ranging from eight to 51 days. Routes will explore the main Mississippi River, as well as its tributaries, including the Tennessee, Cumberland and Ohio Rivers.
Destinations and attractions featured on various itineraries include Graceland, Mark Twain's boyhood home, the St. Louis Arch, Vicksburg National Military Park and Great Smoky Mountains National Park. The company offers themed sailings focused on topics such as Mark Twain, culinary experiences, Civil War history and holiday celebrations.
Cruise packages include pre-cruise hotel stays, shore excursions, onboard enrichment programs, transportation, meals, Wi-Fi, beverages and gratuities. Port charges and fees are also included in the 2025 fares. Domestic airfare is available as an add-on purchase, with complimentary air offered on select sailings.
Editor’s Note: This article was generated by AI, based on a press release distributed by American Cruise Lines. It was fact-checked and reviewed by a TravelAge West editor.
